It was alleged that the girls got a lift from the driver after hitchhiking next to a filling station after writing their exams.
The driver was reported to have lost control as he approached the Matrompi bridge.
Following the incident, Limpopo education MEC Polly Boshielo expressed her shock and sadness.
“The department learnt today [Tuesday] that the learners, four in grade 10 and one in grade 9, met their untimely death … after hiking a lift to take them home,” she said in a statement.
“We are deeply saddened. Our hearts are heavy and we accordingly send our deepest heartfelt condolences to the families of our learners and the school community. This is a very difficult time for all of us, friends and relatives of these learners. We lack the necessary words at this point in time. We must be united in this time of grief.”
The department’s psychosocial unit will provide trauma counselling to the bereaved families, as well as affected pupils, educators and support staff.
Limpopo police commissioner Lt-Gen Nneke Ledwaba condemned the incident and warned drivers not to drink and drive.